Key takeaways

  • IV therapy has shown promise in providing relief for migraines and other forms of headaches.
  • People who use IV therapy tend to report faster relief and improved symptoms.
  • IV therapy delivers medications directly into the bloodstream, offering faster relief compared to oral medications.
  • Research confirms that treatment of refractory migraine requires aggressive intravenous treatment.

Introduction 

IV therapies offer fast and reliable ways to administer medications for chronic conditions, including migraines. In this article, we will look at the possible roles of IV therapy in migraines, as well as its benefits and possible side effects. 

Is IV therapy effective for migraines?

In recent years, IV therapy has emerged as a promising treatment option for migraine sufferers. By administering fluids, electrolytes, and/or medications directly into the bloodstream, this therapy can provide fast relief – often more effectively than oral drugs. One study from 2020 looked at its use among 114 people with migraines: over three-quarters said they felt better after receiving IV infusions during an attack. When managing so-called refractory migraines (those that don’t respond well to standard medications), doctors may also turn to intravenous treatments.  

Another paper published in 2005 noted that giving medicines intravenously allows for rapid titration of doses and precise drug delivery – important factors if high-dose regimens are required acutely without adverse effects such as gastrointestinal irritation.

Benefits of IV therapy for migraines

The benefits of IV therapy for migraines may include:

  • Quick relief: IV treatment sends medication straight into your bloodstream, which works faster than taking drugs by mouth.
  • Hydration: Dehydration can worsen migraine symptoms, but IV fluids help keep you hydrated.
  •  Stronger doses, better results: Because IV treatment allows for high drug doses, you may get more relief from painkillers or anti-sickness medicines than if you took them in pill form.
  • Nutrient replenishment: This is important if you lack certain nutrients that might bring on migraines. IV therapy can put back vitamins and minerals that are low.
  • Treatment customization: Healthcare providers can tailor IV treatments to your symptoms. They’ll change which drugs they use and how much fluid they get based on how bad your migraine is. 

Side effects of IV therapy for migraines

Side effects of IV therapy for migraines are typically minimal but may include:

  •  Discomfort at Injection Site
  •  Allergic Reactions to components of the IV solution or medications administered. This is manifested as itching, rash, swelling, or difficulty breathing.
  •  Nausea and Vomiting
  •  Dizziness or Lightheadedness
  • Fluid Overload
  • Electrolyte Imbalance
  • Inflammation of the vein (phlebitis)
  • Infection at the injection site or along the vein where the IV catheter is placed.
  • In extremely rare cases, more serious complications such as air embolism, nerve injury, or infiltration of IV fluids into surrounding tissues may occur. However, these complications are exceedingly uncommon when IV therapy is performed by trained healthcare professionals using proper techniques and equipment.

Frequently asked questions 

Who can benefit from IV therapy for migraines?

IV treatment for migraines could be helpful to those who have intense migraines, migraine attacks that come with nausea and throwing up, or individuals whose headaches haven’t responded well to oral medications.

What medicines are generally found in IV therapy for migraines?

When used to ease symptoms and bring relief during a migraine episode, IV drugs may comprise pain relievers like NSAIDs or opioids, anti-nausea drugs such as metoclopramide, and triptans specifically designed for migraines.

Is IV therapy safe when it comes to migraines?

For the most part – yes! Healthcare providers who know what they’re doing can give you this treatment without many problems. But remember, medical interventions always have risks (like having an allergic reaction). Or complications from fluids being given too quickly!

Can IVs stop future attacks altogether–or at least make them less frequent?

These treatments won’t stop coming on (or “prevent”) later episodes entirely. They can provide some immediate relief, though–and there are things doctors may suggest if your attacks keep happening often.

I’m pregnant/breastfeeding — could I have IV medication during migraines?

Pregnant or breastfeeding individuals should consult with their healthcare provider before receiving IV therapy for migraines to ensure the safety of the treatment for both themselves and their baby.

Sources

Gelfand, A. A., & Goadsby, P. J. (2012). A Neurologist’s Guide to Acute Migraine Therapy in the Emergency Room. The Neurohospitalist, 2(2), 51-59. https://doi.org/10.1177/1941874412439583

Kandil, M., Jaber, S., Desai, D., Nuñez Cruz, S., Lomotan, N., Ahmad, U., Cirone, M., Burkins, J., & McDowell, M. (2020). MAGraine: Magnesium compared to conventional therapy for treatment of migraines. The American Journal of Emergency Medicine, 39, 28-33. https://doi.org/10.1016/j.ajem.2020.09.033

Soleimanpour, H., Ghafouri, R.R., Taheraghdam, A. et al. Effectiveness of intravenous Dexamethasone versus Propofol for pain relief in the migraine headache: A prospective double blind randomized clinical trial. BMC Neurol 12, 114 (2012). https://doi.org/10.1186/1471-2377-12-114

Shafqat, R., Flores-Montanez, Y., Delbono, V., & Nahas, S. J. (2020). Updated Evaluation of IV Dihydroergotamine (DHE) for Refractory Migraine: Patient Selection and Special Considerations. Journal of Pain Research, 13, 859-864. https://doi.org/10.2147/JPR.S203650

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